LSIDS03:	Listing of Subjects Who Were Unblinded During the Study;  Analysis Set (Study jjcs - core)										
Treatment Group 	Subject ID 	Age (years) / Sex / Race 	Last Visita 	Study Dayb of Unblinding 	Study Dayb of Last Study Agent Administered 	Total Dose (unit)c 	Reason for Unblinding 	Was Study Agent Discontinued? 	Was Study Participation Discontinued Prematurely? 	
Xanomeline High Dose 	01-701-1028 	71 / M / Asian 	Last Treatment Visit 	1 	100 	3661 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1034 	77 / F / White 	Last Treatment Visit 	1 	300 	445 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1146 	75 / F / Unknown 	Last Treatment Visit 	1 	400 	682 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-701-1148 	57 / M / Not reported 	Last Treatment Visit 	1 	100 	3301 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1181 	79 / F / Not reported 	Last Treatment Visit 	1 	200 	3375 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-701-1239 	56 / M / White 	Last Treatment Visit 	1 	400 	723 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1275 	61 / M / White 	Last Treatment Visit 	1 	100 	643 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1287 	56 / F / Multiple 	Last Treatment Visit 	1 	100 	2233 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1302 	61 / M / Asian 	Last Treatment Visit 	1 	400 	1285 [unit] 	Unblind Reason 	Yes 	No 	
 	01-701-1360 	67 / M / Multiple 	Last Treatment Visit 	1 	50 	3744 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-701-1383 	72 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	400 	1592 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1444 	63 / M / American Indian or Alaska Native 	Last Treatment Visit 	1 	100 	3217 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-703-1076 	69 / M / White 	Last Treatment Visit 	1 	50 	4866 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-703-1258 	78 / F / Black or African American 	Last Treatment Visit 	1 	300 	4920 [unit] 	Unblind Reason 	Yes 	No 	
 	01-703-1335 	67 / F / Not reported 	Last Treatment Visit 	1 	300 	4144 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-703-1403 	67 / M / Multiple 	Last Treatment Visit 	1 	200 	4799 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-704-1008 	76 / F / White 	Last Treatment Visit 	1 	300 	1671 [unit] 	Unblind Reason 	No 	No 	
 	01-704-1017 	77 / M / Asian 	Last Treatment Visit 	1 	200 	1561 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-704-1065 	75 / M / Multiple 	Last Treatment Visit 	1 	300 	4487 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-704-1074 	80 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	100 	1741 [unit] 	Unblind Reason 	No 	No 	
 	01-704-1093 	79 / M / American Indian or Alaska Native 	Last Treatment Visit 	1 	400 	1035 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-704-1266 	82 / M / Multiple 	Last Treatment Visit 	1 	300 	3347 [unit] 	Unblind Reason 	Yes 	No 	
 	01-705-1280 	56 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	400 	3394 [unit] 	Unblind Reason 	No 	No 	
 	01-705-1281 	73 / F / Not reported 	Last Treatment Visit 	1 	300 	4016 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-705-1303 	72 / M / Unknown 	Last Treatment Visit 	1 	200 	4880 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-705-1310 	74 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	50 	2580 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-705-1382 	82 / M / Multiple 	Last Treatment Visit 	1 	100 	868 [unit] 	Unblind Reason 	No 	Yes 	
 	01-708-1213 	76 / F / Unknown 	Last Treatment Visit 	1 	200 	4105 [unit] 	Unblind Reason 	No 	Yes 	
 	01-708-1216 	78 / M / Asian 	Last Treatment Visit 	1 	100 	4138 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-708-1236 	86 / F / White 	Last Treatment Visit 	1 	300 	3262 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-708-1336 	73 / M / Other 	Last Treatment Visit 	1 	200 	4927 [unit] 	Unblind Reason 	No 	No 	
 	01-708-1347 	61 / F / White 	Last Treatment Visit 	1 	200 	2169 [unit] 	Unblind Reason 	No 	Yes 	
 	01-708-1372 	84 / M / Not reported 	Last Treatment Visit 	1 	400 	1322 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-709-1099 	79 / F / Multiple 	Last Treatment Visit 	1 	300 	2619 [unit] 	Unblind Reason 	No 	No 	
 	01-709-1168 	72 / F / American Indian or Alaska Native 	Last Treatment Visit 	1 	50 	572 [unit] 	Unblind Reason 	Yes 	No 	
 	01-709-1309 	65 / M / American Indian or Alaska Native 	Last Treatment Visit 	1 	300 	3825 [unit] 	Unblind Reason 	No 	No 	
 	01-709-1329 	70 / M / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	300 	756 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-710-1006 	77 / M / Asian 	Last Treatment Visit 	1 	300 	3309 [unit] 	Unblind Reason 	No 	No 	
 	01-710-1021 	79 / M / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	300 	1225 [unit] 	Unblind Reason 	Yes 	No 	
 	01-710-1137 	79 / F / Multiple 	Last Treatment Visit 	1 	300 	4505 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-710-1142 	76 / F / Not reported 	Last Treatment Visit 	1 	100 	1884 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-710-1187 	78 / F / Unknown 	Last Treatment Visit 	1 	400 	510 [unit] 	Unblind Reason 	No 	No 	
 	01-710-1278 	81 / M / Asian 	Last Treatment Visit 	1 	300 	1435 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-710-1354 	73 / M / Black or African American 	Last Treatment Visit 	1 	200 	3500 [unit] 	Unblind Reason 	No 	No 	
 	01-710-1408 	80 / M / Multiple 	Last Treatment Visit 	1 	50 	298 [unit] 	Unblind Reason 	No 	No 	
 	01-711-1433 	84 / F / Asian 	Last Treatment Visit 	1 	400 	2045 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-713-1141 	79 / M / White 	Last Treatment Visit 	1 	400 	2384 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-714-1288 	77 / M / Multiple 	Last Treatment Visit 	1 	300 	3820 [unit] 	Unblind Reason 	No 	No 	
 	01-714-1425 	81 / M / Black or African American 	Last Treatment Visit 	1 	50 	3686 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-715-1319 	65 / M / Multiple 	Last Treatment Visit 	1 	300 	3797 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-715-1321 	75 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	400 	1625 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-716-1030 	83 / F / Black or African American 	Last Treatment Visit 	1 	400 	3929 [unit] 	Unblind Reason 	No 	No 	
 	01-716-1071 	78 / F / Black or African American 	Last Treatment Visit 	1 	300 	4590 [unit] 	Unblind Reason 	Yes 	No 	
 	01-716-1189 	81 / M / Asian 	Last Treatment Visit 	1 	400 	1369 [unit] 	Unblind Reason 	No 	Yes 	
 	01-716-1229 	73 / F / Asian 	Last Treatment Visit 	1 	200 	3984 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-716-1364 	84 / F / Unknown 	Last Treatment Visit 	1 	200 	4319 [unit] 	Unblind Reason 	No 	No 	
 	01-716-1373 	74 / M / American Indian or Alaska Native 	Last Treatment Visit 	1 	400 	3481 [unit] 	Unblind Reason 	Yes 	No 	
 	01-716-1418 	80 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	200 	2820 [unit] 	Unblind Reason 	No 	No 	
 	01-716-1447 	72 / F / Unknown 	Last Treatment Visit 	1 	400 	4744 [unit] 	Unblind Reason 	No 	No 	
 	01-717-1109 	84 / M / Asian 	Last Treatment Visit 	1 	400 	1523 [unit] 	Unblind Reason 	No 	No 	
 	01-717-1357 	77 / M / White 	Last Treatment Visit 	1 	100 	3353 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-718-1101 	82 / M / Asian 	Last Treatment Visit 	1 	100 	4406 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-718-1328 	86 / M / Not reported 	Last Treatment Visit 	1 	100 	3352 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-718-1371 	69 / F / Unknown 	Last Treatment Visit 	1 	400 	3454 [unit] 	Unblind Reason 	Yes 	Yes 	
Xanomeline Low Dose 	01-701-1033 	74 / M / Multiple 	Last Treatment Visit 	1 	50 	2167 [unit] 	Unblind Reason 	Yes 	No 	
 	01-701-1111 	81 / F / White 	Last Treatment Visit 	1 	200 	2572 [unit] 	Unblind Reason 	No 	Yes 	
 	01-701-1115 	84 / M / Black or African American 	Last Treatment Visit 	1 	400 	3252 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-701-1188 	71 / M / White 	Last Treatment Visit 	1 	100 	933 [unit] 	Unblind Reason 	Yes 	No 	
 	01-701-1192 	80 / F / Not reported 	Last Treatment Visit 	1 	50 	238 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1211 	76 / F / Other 	Last Treatment Visit 	1 	50 	4245 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-701-1294 	67 / M / Other 	Last Treatment Visit 	1 	400 	2017 [unit] 	Unblind Reason 	No 	Yes 	
 	01-701-1317 	68 / M / Unknown 	Last Treatment Visit 	1 	50 	4352 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1324 	79 / M / Asian 	Last Treatment Visit 	1 	200 	4543 [unit] 	Unblind Reason 	No 	No 	
 	01-701-1341 	51 / M / American Indian or Alaska Native 	Last Treatment Visit 	1 	100 	1354 [unit] 	Unblind Reason 	No 	Yes 	
 	01-701-1429 	84 / F / American Indian or Alaska Native 	Last Treatment Visit 	1 	50 	2949 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-701-1442 	57 / F / Asian 	Last Treatment Visit 	1 	200 	1596 [unit] 	Unblind Reason 	No 	No 	
 	01-702-1082 	84 / F / Asian 	Last Treatment Visit 	1 	400 	1244 [unit] 	Unblind Reason 	No 	No 	
 	01-703-1119 	81 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	300 	2288 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-703-1182 	84 / M / Other 	Last Treatment Visit 	1 	300 	2075 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-703-1197 	76 / F / Other 	Last Treatment Visit 	1 	300 	1716 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-703-1279 	72 / F / Unknown 	Last Treatment Visit 	1 	50 	3288 [unit] 	Unblind Reason 	Yes 	No 	
 	01-703-1379 	81 / F / Black or African American 	Last Treatment Visit 	1 	200 	3785 [unit] 	Unblind Reason 	No 	No 	
 	01-704-1009 	83 / M / Unknown 	Last Treatment Visit 	1 	300 	2204 [unit] 	Unblind Reason 	No 	Yes 	
 	01-704-1025 	81 / F / Asian 	Last Treatment Visit 	1 	200 	958 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-704-1114 	77 / M / Multiple 	Last Treatment Visit 	1 	50 	967 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-704-1120 	71 / F / Black or African American 	Last Treatment Visit 	1 	50 	4345 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-704-1135 	74 / F / Black or African American 	Last Treatment Visit 	1 	300 	4027 [unit] 	Unblind Reason 	No 	No 	
 	01-704-1218 	81 / F / American Indian or Alaska Native 	Last Treatment Visit 	1 	200 	3424 [unit] 	Unblind Reason 	No 	No 	
 	01-704-1325 	81 / M / White 	Last Treatment Visit 	1 	300 	4663 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-705-1199 	87 / M / Black or African American 	Last Treatment Visit 	1 	50 	493 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-705-1292 	60 / F / American Indian or Alaska Native 	Last Treatment Visit 	1 	400 	815 [unit] 	Unblind Reason 	No 	No 	
 	01-705-1393 	84 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	300 	3762 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-706-1384 	74 / F / Multiple 	Last Treatment Visit 	1 	50 	4406 [unit] 	Unblind Reason 	No 	No 	
 	01-708-1019 	68 / M / Asian 	Last Treatment Visit 	1 	400 	1177 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-708-1032 	62 / M / Multiple 	Last Treatment Visit 	1 	100 	3770 [unit] 	Unblind Reason 	No 	Yes 	
 	01-708-1272 	82 / M / Not reported 	Last Treatment Visit 	1 	200 	201 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-708-1297 	61 / M / Not reported 	Last Treatment Visit 	1 	300 	3732 [unit] 	Unblind Reason 	Yes 	Yes 	
 	01-708-1348 	79 / F / Multiple 	Last Treatment Visit 	1 	400 	3914 [unit] 	Unblind Reason 	No 	No 	
 	01-708-1353 	87 / F / Native Hawaiian or other Pacific Islander 	Last Treatment Visit 	1 	50 	967 [unit] 	Unblind Reason 	No 	No 	
 	01-709-1081 	86 / F / White 	Last Treatment Visit 	1 	100 	4439 [unit] 	Unblind Reason 	Yes 	Yes 	

a Last visit is the last visit which the subject attended before discontinuing study agent 	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
a Last visit is the last visit which the subject attended before discontinuing study agent	
b Study day is relative to [the start of [study treatment]]. 	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	b Study day is relative to [the start of [study treatment]].	
c Total dose is defined as a cumulative sum of all study agent administered. 	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.	c Total dose is defined as a cumulative sum of all study agent administered.