TSFLAB02:	Subjects With =1 [Laboratory Category] Laboratory Values With Elevated or Low Values Meeting Specified Levels Based on Worst On-treatment Value; Safety Analysis Set (Study jjcs - core)						
 	Active Study Agent 	Active Study Agent 	 	Risk Difference (%) (95% CI) 	Risk Difference (%) (95% CI) 	
Laboratory Test 	Xanomeline High Dose 	Xanomeline Low Dose 	Placebo 	Xanomeline High Dose vs Placebo 	Xanomeline Low Dose vs Placebo 	
  Threshold Level, n (%) 	N=53 	N=73 	N=59 	  	  	
Calcium, low 	 	 	 	 	 	
N 	50 	61 	56 	 	 	
Level 1 (<2.096 mmol/L) 	0 	0 	0 	0.0 (0.0, 0.0) 	0.0 (0.0, 0.0) 	
Level 2 (<1.996 mmol/L) 	17 (34.0%) 	15 (24.6%) 	13 (23.2%) 	10.8 (-6.4, 28.0) 	1.4 (-14.1, 16.8) 	
Level 3 (<1.871 mmol/L) 	0 	0 	0 	0.0 (0.0, 0.0) 	0.0 (0.0, 0.0) 	
 	 	 	 	 	 	
Glucose, low 	 	 	 	 	 	
N 	47 	58 	56 	 	 	
Level 1 (<3.89 mmol/L) 	0 	0 	0 	0.0 (0.0, 0.0) 	0.0 (0.0, 0.0) 	
Level 2 (<3.00 mmol/L) 	0 	0 	0 	0.0 (0.0, 0.0) 	0.0 (0.0, 0.0) 	

Note: On-treatment is defined as treatment-emergent laboratory values obtained after the first dose and within [30 days] following treatment discontinuation. [Treatment-emergent values are those that worsened from baseline.] 	
Note: On-treatment is defined as treatment-emergent laboratory values obtained after the first dose and within [30 days] following treatment discontinuation. [Treatment-emergent values are those that worsened from baseline.]	
Note: On-treatment is defined as treatment-emergent laboratory values obtained after the first dose and within [30 days] following treatment discontinuation. [Treatment-emergent values are those that worsened from baseline.]	
Note: On-treatment is defined as treatment-emergent laboratory values obtained after the first dose and within [30 days] following treatment discontinuation. [Treatment-emergent values are those that worsened from baseline.]	
Note: On-treatment is defined as treatment-emergent laboratory values obtained after the first dose and within [30 days] following treatment discontinuation. [Treatment-emergent values are those that worsened from baseline.]	
Note: On-treatment is defined as treatment-emergent laboratory values obtained after the first dose and within [30 days] following treatment discontinuation. [Treatment-emergent values are those that worsened from baseline.]	
Note: Subjects are counted once per laboratory test category (ie, low, high) based on the worst categorization. 	: Subjects are counted once per laboratory test category (ie, low, high) based on the worst categorization.	: Subjects are counted once per laboratory test category (ie, low, high) based on the worst categorization.	: Subjects are counted once per laboratory test category (ie, low, high) based on the worst categorization.	: Subjects are counted once per laboratory test category (ie, low, high) based on the worst categorization.	: Subjects are counted once per laboratory test category (ie, low, high) based on the worst categorization.