TSFLAB06:	Shift in [Laboratory Category] Laboratory Values From Baseline to [Time Point]; Safety Analysis Set (Study jjcs - core)						
Laboratory Test 	 	Baseline 	Baseline 	Baseline 	Baseline 	
  Study Visit 	N 	Low 	Normal 	High 	Total 	
Xanomeline High Dose 	53 	 	 	 	 	
Xanomeline Low Dose 	73 	 	 	 	 	
Placebo 	59 	 	 	 	 	
 	  	  	  	  	  	
Calcium (mmol/L) 	 	 	 	 	 	
Cycle 02 	 	 	 	 	 	
Xanomeline High Dose 	52 	 	 	 	 	
Low 	 	1 	1 	0 	2 	
Normal 	 	0 	50 	0 	50 	
High 	 	0 	0 	0 	0 	
Total 	 	1 	51 	0 	52 	
 	 	 	 	 	 	
Xanomeline Low Dose 	67 	 	 	 	 	
Low 	 	1 	1 	0 	2 	
Normal 	 	2 	60 	1 	63 	
High 	 	0 	1 	1 	2 	
Total 	 	3 	62 	2 	67 	
 	 	 	 	 	 	
Placebo 	58 	 	 	 	 	
Low 	 	0 	2 	0 	2 	
Normal 	 	1 	55 	0 	56 	
High 	 	0 	0 	0 	0 	
Total 	 	1 	57 	0 	58 	
 	 	 	 	 	 	
Glucose (mmol/L) 	 	 	 	 	 	
Cycle 02 	 	 	 	 	 	
Xanomeline High Dose 	52 	 	 	 	 	
Low 	 	0 	0 	0 	0 	
Normal 	 	0 	49 	0 	49 	
High 	 	0 	3 	0 	3 	
Total 	 	0 	52 	0 	52 	
 	 	 	 	 	 	
Xanomeline Low Dose 	67 	 	 	 	 	
Low 	 	0 	0 	0 	0 	
Normal 	 	0 	66 	0 	66 	
High 	 	0 	1 	0 	1 	
Total 	 	0 	67 	0 	67 	
 	 	 	 	 	 	
Placebo 	57 	 	 	 	 	
Low 	 	0 	0 	0 	0 	
Normal 	 	0 	57 	0 	57 	
High 	 	0 	0 	0 	0 	
Total 	 	0 	57 	0 	57 	
 	 	 	 	 	 	
Potassium (mmol/L) 	 	 	 	 	 	
Cycle 02 	 	 	 	 	 	
Xanomeline High Dose 	51 	 	 	 	 	
Low 	 	0 	0 	0 	0 	
Normal 	 	0 	50 	0 	50 	
High 	 	0 	1 	0 	1 	
Total 	 	0 	51 	0 	51 	
 	 	 	 	 	 	
Xanomeline Low Dose 	67 	 	 	 	 	
Low 	 	0 	1 	0 	1 	
Normal 	 	0 	66 	0 	66 	
High 	 	0 	0 	0 	0 	
Total 	 	0 	67 	0 	67 	
 	 	 	 	 	 	
Placebo 	58 	 	 	 	 	
Low 	 	0 	0 	0 	0 	
Normal 	 	0 	57 	0 	57 	
High 	 	0 	0 	1 	1 	
Total 	 	0 	57 	1 	58 	
 	 	 	 	 	 	
Sodium (mmol/L) 	 	 	 	 	 	
Cycle 02 	 	 	 	 	 	
Xanomeline High Dose 	51 	 	 	 	 	
Low 	 	0 	2 	0 	2 	
Normal 	 	0 	48 	1 	49 	
High 	 	0 	0 	0 	0 	
Total 	 	0 	50 	1 	51 	
 	 	 	 	 	 	
Xanomeline Low Dose 	67 	 	 	 	 	
Low 	 	0 	0 	0 	0 	
Normal 	 	2 	63 	0 	65 	
High 	 	0 	2 	0 	2 	
Total 	 	2 	65 	0 	67 	
 	 	 	 	 	 	
Placebo 	58 	 	 	 	 	
Low 	 	1 	0 	0 	1 	
Normal 	 	0 	52 	3 	55 	
High 	 	0 	2 	0 	2 	
Total 	 	1 	54 	3 	58 	

Note: N is the number of subjects with non-missing values for the lab test at baseline and [Time Point]. 	
Note: N is the number of subjects with non-missing values for the lab test at baseline and [Time Point].	
Note: N is the number of subjects with non-missing values for the lab test at baseline and [Time Point].	
Note: N is the number of subjects with non-missing values for the lab test at baseline and [Time Point].	
Note: N is the number of subjects with non-missing values for the lab test at baseline and [Time Point].	
Note: N is the number of subjects with non-missing values for the lab test at baseline and [Time Point].