TSIMH01:	[Medical History/Medical History of Interest] by System Organ Class and Preferred Term; Full Analysis Set (Study jjcs - core)					
 	Active Study Agent 	Active Study Agent 	 	 	
System Organ Class 	Xanomeline High Dose 	Xanomeline Low Dose 	Placebo 	Total 	
  Preferred Term, n (%) 	N=84 	N=84 	N=86 	N=254 	
Subjects with ≥1 ongoing medical history 	2 (2.4%) 	0 	1 (1.2%) 	3 (1.2%) 	
 	 	 	 	 	
SURGICAL AND MEDICAL PROCEDURES 	1 (1.2%) 	2 (2.4%) 	2 (2.3%) 	5 (2.0%) 	
CATARACT OPERATION 	0 	0 	1 (1.2%) 	1 (0.4%) 	
HERNIA REPAIR 	1 (1.2%) 	0 	0 	1 (0.4%) 	
HIP ARTHROPLASTY 	0 	0 	1 (1.2%) 	1 (0.4%) 	
INTERVERTEBRAL DISC OPERATION 	0 	1 (1.2%) 	0 	1 (0.4%) 	
TOOTH EXTRACTION 	0 	1 (1.2%) 	0 	1 (0.4%) 	
 	 	 	 	 	
INJURY, POISONING AND PROCEDURAL COMPLICATIONS 	0 	0 	2 (2.3%) 	2 (0.8%) 	
SKIN LACERATION 	0 	0 	2 (2.3%) 	2 (0.8%) 	
CONTUSION 	0 	0 	1 (1.2%) 	1 (0.4%) 	
PAIN TRAUMA ACTIVATED 	0 	0 	1 (1.2%) 	1 (0.4%) 	
 	 	 	 	 	
METABOLISM AND NUTRITION DISORDERS 	1 (1.2%) 	0 	1 (1.2%) 	2 (0.8%) 	
HYPERCHOLESTEROLAEMIA 	0 	0 	1 (1.2%) 	1 (0.4%) 	
VITAMIN B12 DEFICIENCY 	1 (1.2%) 	0 	0 	1 (0.4%) 	
 	 	 	 	 	
INFECTIONS AND INFESTATIONS 	0 	0 	1 (1.2%) 	1 (0.4%) 	
NASOPHARYNGITIS 	0 	0 	1 (1.2%) 	1 (0.4%) 	
 	 	 	 	 	
INVESTIGATIONS 	1 (1.2%) 	0 	0 	1 (0.4%) 	
BLOOD PRESSURE INCREASED 	1 (1.2%) 	0 	0 	1 (0.4%) 	

Note: Medical history is coded using MedDRA version 26.0. 	
Note: Medical history is coded using MedDRA version 26.	
Note: Medical history is coded using MedDRA version 26.	
Note: Medical history is coded using MedDRA version 26.	
Note: Medical history is coded using MedDRA version 26.