TSIEX10:	Study Treatment Compliance; Safety Analysis Set (Study jjcs - core)					
 	Active Study Agent 	Active Study Agent 	Active Study Agent 	 	
 	Xanomeline High Dose 	Xanomeline Low Dose 	Combined 	Placebo 	
Parameter 	N=53 	N=73 	N=126 	N=59 	
Compliance (%)a 	 	 	 	 	
N 	53 	73 	126 	59 	
Mean (SD) 	63.7 (35.23) 	66.5 (38.42) 	65.3 (36.99) 	57.0 (36.23) 	
Median 	64.0 	70.0 	68.0 	50.0 	
Min, max 	0, 120 	1, 122 	0, 122 	1, 124 	
 	 	 	 	 	
Compliance a, n (%) 	 	 	 	 	
<60% 	22 (41.5%) 	28 (38.4%) 	50 (39.7%) 	32 (54.2%) 	
60% to <80% 	11 (20.8%) 	13 (17.8%) 	24 (19.0%) 	9 (15.3%) 	
80% to <100% 	8 (15.1%) 	14 (19.2%) 	22 (17.5%) 	8 (13.6%) 	
≥100% 	12 (22.6%) 	18 (24.7%) 	30 (23.8%) 	10 (16.9%) 	

a Compliance is calculated as (actual number of [tablets taken]/total number of [tablets supposed to be taken]) x100 / number of days taking study treatment/total treatment duration [(including days off study treatment)] x100 / (amount dispensed-amount returned)/amount dispensed x100]. 	
a Compliance is calculated as (actual number of [tablets taken]/total number of [tablets supposed to be taken]) x100 / number of days taking study treatment/total treatment duration [(including days off study treatment)] x100 / (amount dispensed-amount returned)/amount dispensed x100].	
a Compliance is calculated as (actual number of [tablets taken]/total number of [tablets supposed to be taken]) x100 / number of days taking study treatment/total treatment duration [(including days off study treatment)] x100 / (amount dispensed-amount returned)/amount dispensed x100].	
a Compliance is calculated as (actual number of [tablets taken]/total number of [tablets supposed to be taken]) x100 / number of days taking study treatment/total treatment duration [(including days off study treatment)] x100 / (amount dispensed-amount returned)/amount dispensed x100].	
a Compliance is calculated as (actual number of [tablets taken]/total number of [tablets supposed to be taken]) x100 / number of days taking study treatment/total treatment duration [(including days off study treatment)] x100 / (amount dispensed-amount returned)/amount dispensed x100].