TSFVIT06:	Subjects With Treatment-emergent Orthostatic Hypotension During [Treatment Period]; Safety Analysis Set (Study jjcs - core)				
 	Active Study Agent 	Active Study Agent 	 	
 	Xanomeline High Dose 	Xanomeline Low Dose 	Placebo 	
Orthostatic hypotension, n (%) 	N=53 	N=73 	N=59 	
N 	28 	39 	37 	
Total number of subjects with orthostatic hypotension 	25 (89.3%) 	33 (84.6%) 	34 (91.9%) 	
DBP (STD-SUP) <-10 	25 (89.3%) 	28 (71.8%) 	32 (86.5%) 	
SBP (STD-SUP) <-20 	19 (67.9%) 	20 (51.3%) 	26 (70.3%) 	

Key: STD=standing, SUP=supine 	
Key: STD=standing, SUP=supine	
Key: STD=standing, SUP=supine	
Key: STD=standing, SUP=supine	
Note: N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline. N includes subjects with missing baseline evaluation. Orthostatic hypotension is defined as an absolute decrease in systolic (>20 mmHg) or diastolic (>10 mmHg) blood pressure after standing for at least 2 minutes relative to supine position. 	: N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline. N includes subjects with missing baseline evaluation. Orthostatic hypotension is defined as an absolute decrease in systolic (>20 mmHg) or diastolic (>10 mmHg) blood pressure after standing for at least 2 minutes relative to supine position.	: N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline. N includes subjects with missing baseline evaluation. Orthostatic hypotension is defined as an absolute decrease in systolic (>20 mmHg) or diastolic (>10 mmHg) blood pressure after standing for at least 2 minutes relative to supine position.	: N is the number of subjects with postbaseline orthostatic measurements and without orthostatic hypotension at baseline. N includes subjects with missing baseline evaluation. Orthostatic hypotension is defined as an absolute decrease in systolic (>20 mmHg) or diastolic (>10 mmHg) blood pressure after standing for at least 2 minutes relative to supine position.