Get boundary specifications for group sequential design

Usage

get_boundaries(
  dist_type,
  control,
  test,
  sf,
  sfpar,
  nominal,
  enroll_rate,
  distribution,
  possible_weight,
  control_pooled_rate,
  test_pooled_rate,
  information_factor,
  max_information_factor,
  information_fractions,
  times_analysed = NULL,
  alpha = 0.025
)

Arguments

dist_type: Type of endpoint (binary or time-to-event)
control: Control treatment character string
test: Test treatment character string
sf: Spending function string (in rpact terminology)
sfpar: Spending function parameter (if needed)
nominal: Nominal spend information (if using)
enroll_rate: Enrollment rate object
distribution: Distributional information object
possible_weight: Weight in the analysis (from the graphical test)
control_pooled_rate: Control arm pooled rate (for binary outcomes)
test_pooled_rate: Test arm pooled rate (for binary outcomes)
information_factor: Information factors (either ubjects or events)
max_information_factor: Maximum information factor (either max subjects or max events)
information_fractions: Information fractions across the analyses
times_analysed: Analysis times (for time-to-event endpoints)
alpha: Type I error rate

Value

Boundary specifications object